Description
CD40, also known as tumor necrosis factor receptor superfamily member, is receptor for TNFSF5/CD40LG. It transduces TRAF6 and MAP3K8 mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. Recombinant mouse CD40, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques